From left: Marc Packman of Trinity Real Estate and 200 Hudson Street

Midtown South, which already has the lowest vacancy rate of any market in the country for office space, is nurturing a hub for New York City’s tenants du jour — the creative class — and the rents look almost pre-recession there.

The Hudson Square submarket — which runs from Canal to 14th streets, and from Sixth Avenue to the Hudson River — saw the largest decline in vacancy rate and the biggest spike in asking rents of any neighborhood in Midtown South year-over-year, according to Cushman & Wakefield’s fourth-quarter numbers, unveiled at a media breakfast yesterday. [more]