One Lincoln Plaza at 20 West 64th Street is a high rise, mixed-use, apartment and commercial building in the Lincoln Square neighborhood of the Upper West Side in Manhattan. It was built in 1972 and designed by architects at Phil Birnbaum & Associates in the modernist style. The building is 490 feet tall and contains 968,442 square feet. It is currently serves as the headquarters of the Screen Actors Guild, who signed a 55,000-square-foot, $50 million lease in 2013. A 3,000-square-foot apartment listed for $26,600 a month in 2014. The building is owned and operated by Ogden CAP.

The skyscraper made headlines in 2012 after the suicide of popular soap opera actor Nick Santino was allegedly connected to One Lincoln Plazas restrictive pet policies. Friends of Santino said that he euthanized his pit bull the day of his eventual suicide in order to avoid harassment by the co-op, who had recently required pit bull owners to use the service elevator.