The company inked a 16-year deal for 91,000 square feet on the 45-story tower’s 15th, 16th and 17th floors, Crain’s reported.
Duff & Phelps occupies 62,413 square feet of space on a sublease with the insurance firm AON.
“It is always a source of pride when blue-chip firms like Duff & Phelps and Evercore transition from a sublease to a direct, long-term relationship,” Fisher Brothers partner Winston Fisher said in a statement.
Savills Studley brokers Mike Catalano, Greg Taubin and Pete Cento represented Duff & Phelps in the deal.
The deal helps stem the flow of tenants leaving the 1.2 million-square-foot building at 55 East 52nd Street.