The site, at 656 and 660 Stanford Avenue, is currently occupied by a 50-unit single room occupancy building dating back to 1912. The property last changed hands in 1990.
The project requires a general plan amendment as well as a zoning change from manufacturing to commercial. There are currently 42 tenants in the building who will need to be relocated, according to city documents.
The project would not be subject to the two-year development moratorium imposed by Measure S, since it would comprise solely affordable housing.
A spokesperson for LAMP, which operates a handful of housing and homeless service facilities in the Downtown area, could not be immediately reached for comment on the plans.
LAMP also operates a 98-bed shelter called known as the Village at 527 Crocker Street.
The project is one of a number slated to transform the troubled area in and around Skid Row. Another nonprofit, the Weingart Center Association, recently filed plans for multifamily buildings comprising 407 units on the block bound by San Pedro and Crocker Streets along E 6th Street. The Skid Row Housing Trust has also filed plans for a 14-story, 151-unit affordable housing complex at 609-623 E 5th Street.